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Peer-reviewed veterinary case report

Labrador dog with rare gum tumor called odontogenic myxoma

By Barigye, Robert et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2011·Department of Veterinary and Microbiological Sciences, United States·View original on PubMed

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Original publication title: Odontogenic myxoma in an 8-year-old Labrador Retriever dog.

Species:
dog
Canine mammary tumorsBehaviour & energyDogs

Plain-English summary

An 8-year-old Labrador Retriever was diagnosed with a rare type of tumor called odontogenic myxoma after the owner noticed an unusual, bleeding mass in the dog's mouth. The mass was located on the gums and showed specific cell characteristics under the microscope. While this type of tumor can be aggressive and grow slowly, the exact outcome for this dog is still unclear. Treatment options were not detailed, but early detection is important for managing this condition.

People also search for: dog mouth tumor · Labrador Retriever gum mass · odontogenic myxoma in dogs

Abstract

Odontogenic myxoma (OM) was diagnosed in an 8-year-old Labrador Retriever dog with an ulcerohemorrhagic mass located on the caudal area of the right maxillary gingiva. The neoplasm was characterized by a low mitotic index and moderate numbers of spindle, stellate, and round cells that were sparsely distributed in an alcian blue reactive myxomatous matrix. Individual neoplastic cells were characterized by small amounts of faintly eosinophilic staining cytoplasm, prominent nucleoli, and stippled amphophilic staining chromatin that was immunoreactive for vimentin but negative for cytokeratin and actin. To the authors' knowledge, this is the first reported case of canine OM from North America, and it shares histomorphologic and histochemical features with 3 other cases reported in dogs elsewhere. Whereas, a literature review suggests untreated canine OM is insidious and locally aggressive, the prognosis in the present dog remains unknown. These findings support previous recommendations for inclusion of canine OM on the World Health Organization list of odontogenic tumors.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21217053/