Peer-reviewed veterinary case report
Bone marrow failure from estrogen in a dog with Sertoli tumor
By Sanpera, N et al.·Published in The Journal of small animal practice·2002·Hospital Veterinari Via Aurè, Spain·View original on PubMed →
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Original publication title: Oestrogen-induced bone marrow aplasia in a dog with a Sertoli cell tumour.
- Species:
- dog
Plain-English summary
A 10-year-old male Drahthaar dog was brought to the vet because he was showing signs of feminization and had low blood cell counts. Imaging tests found an abdominal mass, which turned out to be a Sertoli cell tumor, a type of testicular tumor that can produce hormones. Despite surgery to remove the tumor and aggressive treatment with fluids, antibiotics, blood transfusions, and steroids, the dog did not recover and lived for only 22 days after the surgery.
People also search for: dog feminization symptoms · Sertoli cell tumor in dogs · dog low blood cell count treatment
Abstract
A 10-year-old male Drahthaar dog with unilateral cryptorchidism was examined because of feminisation and myelotoxicity. Radiography and ultrasonography revealed an abdominal mass which was surgically removed. The mass was identified as a Sertoli cell tumour on histological examination. Findings on bone marrow examination were compatible with aplasia due to the oestrogens secreted by the tumoral cells. Treatment with fluids, antibiotics, whole blood transfusions, corticosteroids and lithium carbonate was unsuccessful. Survival time was 22 days after surgery.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12201446/