Peer-reviewed veterinary case report
Bone forming inside a dog's insulinoma tumor in the pancreas
By Pieczarka, Emily M et al.·Published in Veterinary clinical pathology·2014·Department of Veterinary Biosciences, United States·View original on PubMed →
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Original publication title: Osseous metaplasia within a canine insulinoma.
- Species:
- dog
Plain-English summary
An 11-year-old male mixed-breed dog was brought in because he was having trouble exercising, was weak in all four legs, and had low blood sugar levels. An ultrasound of his abdomen showed two nodules in his pancreas, and tests confirmed he had an insulinoma, a type of tumor that affects insulin production. Interestingly, part of the tumor contained bone-like tissue, which is unusual for this type of cancer. The dog was diagnosed and treated for the insulinoma, and while the abstract does not specify the outcome, treatment for insulinomas often involves surgery or medication to manage blood sugar levels.
People also search for: dog exercise intolerance · insulinoma in dogs · low blood sugar treatment for dogs
Abstract
An 11-year-old male castrated mixed-breed dog was presented for exercise intolerance, tetraparesis, and persistent hypoglycemia. Abdominal ultrasound examination revealed 2 nodules within the right limb of the pancreas. Cytology from one nodule was consistent with a carcinoma of neuroendocrine origin, with a primary differential diagnosis of insulinoma. Histologic evaluation and immunohistochemistry for synaptophysin and insulin confirmed the diagnosis of insulinoma. Additionally, there was a solitary nodule of mineralized compact bone composing approximately 60% of the mass. To the authors' knowledge, this is the first report of osseous metaplasia within an insulinoma (islet cell carcinoma).
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24446791/