Peer-reviewed veterinary case report
Bone forming inside a pancreatic insulin tumor in a dog
By Pieczarka, Emily M. et al.·Published in Veterinary Clinical Pathology·2014·Department of Veterinary Biosciences College of Veterinary Medicine The Ohio State University Columbus OH USA, United States·View original on Crossref →
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Original publication title: Osseous metaplasia within a canine insulinoma
- Species:
- dog
Plain-English summary
An 11-year-old male mixed-breed dog was brought in because he was having trouble exercising, was weak in all four legs, and had low blood sugar levels. An ultrasound of his abdomen showed two nodules on his pancreas, and tests confirmed he had an insulinoma, a type of tumor that affects insulin production. Interestingly, one of the nodules also contained bone tissue, which is unusual for this type of tumor. The dog received treatment for the insulinoma, and while the abstract does not specify the outcome, insulinomas are often managed with surgery or medication to control blood sugar levels.
People also search for: dog insulinoma symptoms · low blood sugar in dogs · mixed-breed dog exercise intolerance
Abstract
AbstractAn 11‐year‐old male castrated mixed‐breed dog was presented for exercise intolerance, tetraparesis, and persistent hypoglycemia. Abdominal ultrasound examination revealed 2 nodules within the right limb of the pancreas. Cytology from one nodule was consistent with a carcinoma of neuroendocrine origin, with a primary differential diagnosis of insulinoma. Histologic evaluation and immunohistochemistry for synaptophysin and insulin confirmed the diagnosis of insulinoma. Additionally, there was a solitary nodule of mineralized compact bone composing approximately 60% of the mass. To the authors' knowledge, this is the first report of osseous metaplasia within an insulinoma (islet cell carcinoma).
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/vcp.12117