Peer-reviewed veterinary case report
Dog with large ovarian tumor causing belly swelling and tiredness
By Robinson, Nicholas A et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2013·Department of Veterinary Population Medicine and Veterinary Diagnostic Laboratory, United States·View original on PubMed →
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Original publication title: Ovarian mixed germ cell tumor with yolk sac and teratomatous components in a dog.
- Species:
- dog
Plain-English summary
A 3-year-old female Labrador Retriever was brought to the vet because she was lethargic, had a swollen belly, and a noticeable mass in her abdomen. During surgery, the vet found a large tumor on her left ovary and several smaller masses in her abdomen. Tests showed that the tumor was a mixed germ cell tumor, which included components that resembled both yolk sac tissue and nerve tissue. After surgery, the dog was treated for the tumor, and the specific details of her recovery were not provided, but the diagnosis helps guide future treatment options.
People also search for: dog ovarian tumor symptoms · Labrador Retriever abdominal mass · dog lethargy and swelling treatment
Abstract
Mixed germ cell tumors of the ovary have rarely been reported in veterinary species. A 3-year-old intact female Labrador Retriever dog was presented for lethargy, abdominal distention, and a midabdominal mass. An exploratory laparotomy revealed a large (23 cm in diameter) left ovarian tumor and multiple small (2-3 cm in diameter) pale tan masses on the peritoneum and abdominal surface of the diaphragm. Histological examination of the left ovary revealed a mixed germ cell tumor with a yolk sac component with rare Schiller-Duval bodies and a teratomatous component comprised primarily of neural differentiation. The abdominal metastases were solely comprised of the yolk sac component. The yolk sac component was diffusely immunopositive for cytokeratin with scattered cells reactive for α-fetoprotein and placental alkaline phosphatase. Within the teratomatous component, the neuropil was diffusely immunopositive for S100, neuron-specific enolase, and neurofilaments with a few glial fibrillary acidic protein immunopositive cells. Ovarian germ cell tumors may be pure and consist of only 1 germ cell element or may be mixed and include more than 1 germ cell element, such as teratoma and yolk sac tumor.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23604259/