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Peer-reviewed veterinary case report

Ovarian neuroglial tumor found in 5-year-old dog

By Lee, Na-Young et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2025·Laboratory of Veterinary Pathology and Research Institute of Veterinary Science, South Korea·View original on PubMed

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Original publication title: Ovarian neuroglial choristoma in a dog.

Species:
dog

Plain-English summary

A 5-year-old female mixed-breed dog was found to have an unusual mass on her ovary during a routine check-up. The mass was made up of cells that looked like nerve cells and supportive brain cells. After further testing, the veterinarian diagnosed it as an ovarian neuroglial choristoma, which is a rare type of tumor. While the abstract does not specify treatment or outcome, it's important for pet owners to discuss any findings of masses with their veterinarian for appropriate care and management.

People also search for: dog ovarian mass · mixed-breed dog tumor · ovarian neuroglial choristoma treatment

Abstract

Neuroglial choristomas are rare in humans and animals. During a routine medical examination, an ovarian mass was found in a 5-y-old female mixed-breed dog. Histologically, the ovarian mass was well-defined, expansile, and composed of large polygonal cells resembling well-differentiated neurons and scattered smaller cells resembling glial cells. Immunohistochemically, the neuron-like cells were positive for neuronal nuclei; the smaller cells were positive for glial fibrillar acidic protein, oligodendrocyte transcription factor 2, and ionized calcium-binding adaptor protein-1. Ovarian neuroglial choristoma was diagnosed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39895013/