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Peer-reviewed veterinary case report

Risk factors and genetics of Mycoplasma turicensis infection in pet

By Willi, Barbara et al.·Published in Journal of clinical microbiology·2006·Vetsuisse-Faculty·View original on PubMed

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Original publication title: Phylogenetic analysis of "Candidatus Mycoplasma turicensis" isolates from pet cats in the United Kingdom, Australia, and South Africa, with analysis of risk factors for infection.

Species:
cat

Plain-English summary

A group of pet cats from the UK, Australia, and South Africa were tested for a newly identified blood infection called "Candidatus Mycoplasma turicensis," which can cause anemia. The study found that male cats and those also infected with other types of hemoplasmas had lower red blood cell counts. This infection appears to be widespread in these regions, and cats with multiple infections showed more severe symptoms. If your cat is showing signs of anemia, such as weakness or lethargy, it’s important to discuss testing for this infection with your veterinarian.

People also search for: cat anemia symptoms · Mycoplasma turicensis infection in cats · male cat blood infection treatment

Abstract

Two hemotropic mycoplasmas have been recognized in cats, Mycoplasma haemofelis and "Candidatus Mycoplasma haemominutum." We recently described a third feline hemoplasma species, designated "Candidatus Mycoplasma turicensis," in a Swiss cat with hemolytic anemia. This isolate induced anemia after experimental transmission to two specific-pathogen-free cats and analysis of the 16S rRNA gene revealed its close relationship to rodent hemotropic mycoplasmas. The agent was recently shown to be prevalent in Swiss pet cats. We sought to investigate the presence and clinical importance of "Candidatus Mycoplasma turicensis" infection in pet cats outside of Switzerland and to perform the molecular characterization of isolates from different countries. A "Candidatus Mycoplasma turicensis"-specific real-time PCR assay was applied to blood samples from 426 United Kingdom (UK), 147 Australian, and 69 South African pet cats. The 16S rRNA genes of isolates from different countries were sequenced and signalment and laboratory data for the cats were evaluated for associations with "Candidatus Mycoplasma turicensis" infection. Infections were detected in samples from UK, Australian, and South African pet cats. Infection was associated with the male gender, and "Candidatus Mycoplasma haemominutum" and M. haemofelis coinfection. Coinfected cats exhibited significantly lower packed cell volume (PCV) values than uninfected cats. Phylogenetic analyses revealed that some Australian and South African "Candidatus Mycoplasma turicensis" isolates branched away from the remaining isolates. In summary, "Candidatus Mycoplasma turicensis" infection in pet cats exists over a wide geographical area and significantly decreased PCV values are observed in cats coinfected with other feline hemoplasmas.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17035497/