Peer-reviewed veterinary case report
Placement of a subcutaneous ureteral bypass in a Miniature Pinscher with presumed xanthine urolithiasis as a result of allopurinol treatment.
- Journal:
- Schweizer Archiv fur Tierheilkunde
- Year:
- 2024
- Authors:
- Gloor, C et al.
- Affiliation:
- Department for Clinical Veterinary Medicine
- Species:
- dog
Plain-English summary
A Miniature Pinscher was treated for a blockage in its ureters, which are tubes that carry urine from the kidneys to the bladder. This blockage was likely caused by xanthine stones, a side effect of a medication called allopurinol that was used to treat leishmaniasis, a parasitic disease. The dog showed signs of being very tired, not urinating, and had abdominal pain. After placing a subcutaneous ureteral bypass device to help drain urine, the dog recovered well, and its kidney function improved quickly. Over three years of follow-up, there were no complications, and the treatment was deemed successful and safe.
Abstract
This case report describes the long-term success of a subcutaneous ureteral bypass device in a dog for treatment of a ureteral obstruction. The suspected xanthine urolithiasis was secondary to treatment with allopurinol for leishmaniasis. The dog presented initially with lethargy, anuria and abdominal pain. Mild azotemia was found on biochemical analysis and abdominal ultrasound revealed bilateral ureteral obstruction. A subcutaneous ureteral bypass was subsequently placed using a standard surgical technique. The dog recovered uneventfully and the azotemia resolved within days. Follow-up examinations were performed every trimester for over three years and no complications like obstruction of the bypass tubes, urinary tract infection or azotemia were recognized during this follow-up period. Allopurinol was replaced with domperidone as long-term treatment against Leishmaniasis which resulted in a mild increase of the leishmania serum antibody titer. The subcutaneous ureteral bypass placement was successful and safe in this dog and is a valuable alternative in cases of ureteral obstruction also in dogs.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/38572822/