Peer-reviewed veterinary case report
Outcome after surgery for mammary tumors in 134 dogs
By Betz, D et al.·Published in Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·2012·Small Animal Hospital, Germany·View original on PubMed →
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Original publication title: Postoperative treatment outcome in canine mammary tumors. Multivariate analysis of the prognostic value of pre- and postoperatively available information.
- Species:
- dog
Plain-English summary
A group of 134 dogs with mammary tumors underwent surgery to remove the tumors, and their outcomes were tracked afterward. The study found that the type of tumor (benign or malignant) significantly affected survival rates, with benign tumors having the best outcomes. Dogs with malignant tumors had shorter survival times, and factors like tumor grade and cytology results before surgery were important in predicting how well the dogs would do after treatment. Overall, the findings suggest that understanding the tumor's characteristics can help veterinarians predict recovery and recurrence chances after surgery.
People also search for: dog mammary tumor surgery outcome · canine mammary tumor survival rate · dog tumor grade prognosis
Abstract
OBJECTIVE: Mammary tumors belong to the most common canine neoplasias. Few data are available on postoperative outcome and independent prognostic value of variables including pre-operatively available parameters such as cytology. The aim of this study was to characterize outcome following surgery and identify independent prognostic factors in canine mammary tumors. MATERIAL AND METHODS: Prospective study in which dogs with mammary tumors underwent surgical tumor removal followed by histopathologic examination of the neoplasias. Kaplan-Meier log rank analysis and multivariate regression analyses were used to evaluate survival, recurrence-free interval (RFI) and metastasis free interval (MFI) as well as independent influence of variables on outcome. RESULTS: 134 dogs with mammary tumors were included. In 126 dogs without distant metastasis, overall survival duration was 1113 d; median RFI and MFI were not reached. Histologic grade showed independent influence on duration of RFI (p=0.040), MFI (p=0.007), and survival (p=0.029). Median survival in benign (n=98), grade 1 (n=10) and grade 2 (n=16) malignant tumors was 1319 d, 670 d, 406 d, respectively. Cytology exerted independent influence on the likelihood for recurrence (p=0.013), duration of RFI (p=0.026) and survival (p=0.030). CONCLUSION AND CLINICAL RELEVANCE: Histologic grade was of independent prognostic significance for postoperative outcome in this population of dogs with mammary tumors. As a pre-operatively available parameter, cytology may also possess prognostic value in canine mammary neoplasias.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22911254/