Peer-reviewed veterinary case report
CT scans show nasal transmissible venereal tumor
By Patsikas, M et al.·Published in Journal of biological regulators and homeostatic agents·2018·School of Veterinary Medicine·View original on PubMed →
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Original publication title: Pre- and post-treatment computed tomographic findings of a primary intranasal transmissible venereal tumor in a canine patient.
- Species:
- dog
Plain-English summary
A 2-year-old female cross-breed dog had a two-month history of nasal discharge and was found to have a transmissible venereal tumor in her nose. A CT scan showed significant damage to her nasal structures and bones. After treatment with vincristine (a chemotherapy drug) and antibiotics, the dog was doing well three months later, with no signs of the tumor on follow-up scans. While some bone damage remained, her nasal passages were clear and filled with air, indicating recovery.
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Abstract
A two-year-old, female intact, cross-breed dog presented with a two-month history of nasal discharge. Computed tomography (CT) demonstrated obliteration of both nasal cavities by soft tissue density, destruction of the nasal and ethmoidal turbinates, and lysis of the frontal and palatine bones and maxilla. Frontal sinuses and maxillary recesses were obscured by soft tissue/fluid density. Histopathological examination of the mass was diagnostic of transmissible venereal tumor. The dog was clinically normal 3 months after treatment initiation with vincristine sulphate and amoxicillin/clavulanate. Six months after the completion of treatment no mass-like lesion was demonstrated in CT sections. Nasal cavities, maxillary recesses and frontal sinuses were filled with air. The reticular turbinate nasal plexus appeared atrophic with focal loss of the nasal turbinates on both sides. The ethmoidal turbinates were well-defined; however, focal loss of turbinates was also seen. Lysis of the frontal and palatine bones were still evident.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29921382/