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Peer-reviewed veterinary case report

Cystic lymphangioma tumor found in adult dog's spleen

By Ramírez, G A et al.·Published in Journal of comparative pathology·2020·Department of Animal Science, Spain·View original on PubMed

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Original publication title: Primary Cystic Lymphangioma of the Spleen in an Adult Dog.

Species:
dog

Plain-English summary

A 7-year-old female mixed-breed dog was brought to the vet because she was lethargic and not eating well. An ultrasound of her abdomen showed an enlarged spleen with a fluid-filled lesion. The vet performed surgery to remove the spleen, and tests revealed that the lesion was a rare type of tumor called cystic lymphangioma. This condition is unusual in dogs, especially in the spleen, but the surgery was successful, and the dog was treated for her symptoms.

People also search for: dog not eating · lethargic dog symptoms · splenic tumor in dogs · cystic lymphangioma treatment

Abstract

Proliferative disorders of lymphatic origin in animals are mostly congenital or occur within the first few months of life. Involvement of internal organs is extremely infrequent. A seven-year-old entire female mixed-breed dog was presented with apathy and poor appetite. Abdominal ultrasonography revealed a focally enlarged spleen with an anechoic round lesion. Splenectomy was performed and pathological examination demonstrated a sponge-like, compressible tumour composed of endothelium-lined vascular cystic spaces filled with eosinophilic proteinaceous material lacking erythrocytes. Immunohistochemical stains showed that cyst-lining cells were strongly positive for CD31 and factor VIII and focally positive for lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1). Based on these findings, the lesion was identified as splenic cystic lymphangioma. To the best of our knowledge, this is the first description of solitary lymphangioma of the spleen in animals.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32800104/