Peer-reviewed veterinary case report
Primary meningeal lymphoma in a horse.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1992
- Authors:
- Lester, G D et al.
- Affiliation:
- Department of Large Animal Clinical Sciences · United States
- Species:
- horse
Plain-English summary
An 18-year-old Morgan gelding was diagnosed with primary meningeal lymphoma, a type of cancer affecting the protective membranes of the brain and spinal cord. The horse had been showing signs of weakness and trouble walking for three days, with more noticeable issues on the left side of his body. He also appeared depressed, had a smaller left pupil, a droopy left eyelid, and some muscle wasting on the left side of his neck and shoulder. Tests of the fluid around his brain and spinal cord showed inflammation, and during the examination after he passed away, there was thickening of the protective layer around his spinal cord. Unfortunately, the treatment did not work, and the horse's condition was severe.
Abstract
Primary meningeal lymphoma was diagnosed in an 18-year-old Morgan gelding. The horse was examined because of a 3-day history of progressive ataxia and weakness. The gait abnormalities were worse on the left side, and the pelvic limbs were more affected than the thoracic limbs. Additional findings included signs of depression, miosis of the left pupil, ptosis of the left upper eyelid, and areas of muscle atrophy on the left side of the neck and over the dorsal aspect of the left scapula. Inflammatory changes were evident in the CSF. At necropsy, there was diffuse and irregular thickening of the dura mater along the entire spinal cord. Histologic examination revealed infiltration of the leptomeninges with neoplastic lymphocytes.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/1429163/