Peer-reviewed veterinary case report
Ovarian cancer with abdominal spread in a 10-year-old English pointer
By Boeloni, J N et al.·Published in Journal of comparative pathology·2012·Laborató, Brazil·View original on PubMed →
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Original publication title: Primary ovarian rhabdomyosarcoma in a dog.
- Species:
- dog
Plain-English summary
A 10-year-old female English pointer was found to have an ovarian tumor that had spread to her abdomen. Ultrasound showed several nodules ranging from 1 to 5 cm in size, and tests indicated that these nodules were likely a malignant tumor. Sadly, during a necropsy, it was confirmed that the tumor had caused significant damage, with masses found on various organs including the pancreas and liver. The diagnosis was primary ovarian rhabdomyosarcoma, a type of cancer. Unfortunately, due to the advanced stage of the disease, treatment options were limited, and the prognosis was poor.
People also search for: dog ovarian tumor symptoms · English pointer cancer treatment · dog abdominal mass diagnosis
Abstract
A 10-year-old female English pointer was diagnosed with an ovarian tumour with abdominal metastases. Ultrasonography revealed several nodules of 1-5 cm diameter within the abdominal cavity. Fine needle aspiration cytology of the nodules suggested a malignant mesenchymal tumour. On necropsy examination the right ovary and its capsule were enlarged and there were white-red, friable nodular masses distributed over the surface of the pancreas, liver, omentum, mesentery and serosae of the small and large intestines. Microscopical evaluation revealed neoplastic cells with a high degree of pleomorphism and vascular invasion. Immunohistochemically, the neoplastic cells expressed myosin, desmin, vimentin and CD10, but were negative for cytokeratin, placental alkaline phosphatase, inhibin-alpha and smooth muscle actin. Based on these findings a diagnosis of primary ovarian alveolar rhabdomyosarcoma was made.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22878055/