Peer-reviewed veterinary case report
Probing bacterial pathogenesis with genetics, genomics, and chemical biology: past, present, and future approaches.
- Journal:
- Critical reviews in biochemistry and molecular biology
- Year:
- 2011
- Authors:
- Gomez, James E et al.
- Affiliation:
- The Broad Institute of MIT and Harvard · United States
Abstract
Classical genetic approaches for studying bacterial pathogenesis have provided a solid foundation for our current understanding of microbial physiology and the interactions between pathogen and host. During the past decade however, advances in several arenas have expanded the ways in which the biology of pathogens can be studied. This review discussed the impact of these advances on bacterial genetics, including the application of genomics and chemical biology to the study of pathogenesis.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21250782/