Peer-reviewed veterinary case report
Measuring dog skin tumor cells to tell cancer from scars
By Simeonov, R. et al.·Published in Veterinary and Comparative Oncology·2014·Department of General and Clinical Pathology, Faculty of Veterinary Medicine Trakia University Stara Zagora Bulgaria·View original on Crossref →
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Original publication title: Quantitative morphology in canine cutaneous soft tissue sarcomas
- Species:
- dog
Plain-English summary
A group of 24 dogs with soft tissue tumors, including fibrosarcoma, liposarcoma, and hemangiopericytoma, were examined to see if their tumors could be distinguished from other tissue growths using advanced imaging techniques. The study found that the characteristics of the tumor cells were different from those of reactive tissue lesions, which can help veterinarians identify the type of growth. However, the different types of soft tissue sarcomas did not show significant differences from each other. This research suggests that while we can differentiate between tumors and other tissue issues, more work is needed to tell apart the various types of soft tissue sarcomas in dogs.
People also search for: dog soft tissue sarcoma symptoms · how to tell if my dog has a tumor · treatment options for dog fibrosarcoma
Abstract
AbstractStained cytological specimens from 24 dogs with spontaneous soft tissue sarcomas [fibrosarcoma (n = 8), liposarcoma (n = 8) and haemangiopericytoma (n = 8)], and 24 dogs with reactive connective tissue lesions [granulation tissue (n = 12) and dermal fibrosis (n = 12)] were analysed by computer‐assisted nuclear morphometry. The studied morphometric parameters were: mean nuclear area (MNA; µm2), mean nuclear perimeter (MNP; µm), mean nuclear diameter (MNDmean; µm), minimum nuclear diameter (Dmin; µm) and maximum nuclear diameter (Dmax; µm). The study aimed to evaluate (1) possibility for quantitative differentiation of soft tissue sarcomas from reactive connective tissue lesions and (2) by using cytomorphometry, to differentiate the various histopathological soft tissue sarcomas subtypes in dogs. The mean values of all nuclear cytomorphometric parameters (except for Dmax) were statistically significantly higher in reactive connective tissue processes than in soft tissue sarcomas. At the same time, however, there were no considerable differences among the different sarcoma subtypes. The results demonstrated that the quantitative differentiation of reactive connective tissue processes from soft tissue sarcomas in dogs is possible, but the same was not true for the different canine soft tissue sarcoma subtypes. Further investigations on this topic are necessary for thorough explication of the role of quantitative morphology in the diagnostics of mesenchymal neoplasms and tumour‐like fibrous lesions in dogs
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/vco.12099