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Peer-reviewed veterinary case report

Detecting feline herpesvirus and calicivirus after cat vaccines

By Ruch-Gallie, Rebecca A et al.·Published in Journal of feline medicine and surgery·2011·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Results of molecular diagnostic assays targeting feline herpesvirus-1 and feline calicivirus in adult cats administered modified live vaccines.

Species:
cat

Plain-English summary

Twelve adult cats that had been previously exposed to feline herpesvirus-1 (FHV-1) and/or vaccinated against feline calicivirus (FCV) were studied to see how well a new vaccine worked. The cats were tested for these viruses before and after receiving the vaccine. Results showed that only a few cats had detectable levels of FHV-1 and FCV both before and after vaccination, indicating that the vaccine did not lead to a significant increase in these viruses. Overall, the findings suggest that the vaccine was effective in keeping the virus levels low in these cats.

People also search for: cat herpesvirus vaccine effectiveness · feline calicivirus symptoms · adult cat vaccination schedule

Abstract

In this pilot study, 12 adult, gang-housed cats that were known to be previously exposed (n=12) to feline herpesvirus-1 (FHV-1) and/or vaccinated against (n=2) feline calicivirus (FCV) and FHV-1 were randomly assigned to one of two groups of six cats each. Nasal and pharyngeal samples were collected from each cat on days -7, -3, and 0 prior to vaccination and on days 3, 7, 10, 14, 17, 21, and 28 after vaccination with an FHV-1, FCV, and panleukopenia (FVRCP) vaccine developed for intranasal (six cats) or parenteral (six cats) use. FHV-1 DNA was amplified from 1/12 cats (1/69 samples; 1.4%) prior to vaccination and 2/12 cats after vaccination (2/154 samples; 1.3%). FCV RNA was amplified from 2/12 cats (2/69 samples; 2.9%) prior to vaccination and 7/12 cats (12/154 samples; 7.8%) after vaccination. Positive molecular diagnostic assay results for FHV-1 and FCV were uncommon prior to or after vaccination in these cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21439879/