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Peer-reviewed veterinary case report

Dog diagnosed with rare mucinous testicular cancer after surgery

By Radi, Z A et al.·Published in Veterinary pathology·2004·The University of Georgia, United States·View original on PubMed

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Original publication title: Rete testis mucinous adenocarcinoma in a dog.

Species:
dog

Plain-English summary

A mixed-breed male dog, 11 years old, was diagnosed with a rare type of testicular cancer called mucinous adenocarcinoma after surgery to remove a tumor from his testicles. The tumor was examined and found to have abnormal cells that produced a lot of mucus. This type of cancer is uncommon in dogs and has not been reported before in this specific form. The dog underwent surgery to remove the tumor, but the abstract does not provide details on his recovery or any further treatment.

People also search for: dog testicular cancer symptoms · mixed-breed dog surgery recovery · mucinous adenocarcinoma in dogs

Abstract

A bilateral testicular neoplasm from an 11-year-old mixed-breed male dog was removed surgically and examined histologically. The neoplasm was nonencapsulated and composed of acinar and tubular structures lined by one or more layers of neoplastic polyhedral epithelial cells with an abundant mucinous secretion. On histochemistry, all neoplastic cells and associated secretions were periodic acid-Schiff positive. Some neoplastic cells and all associated secretions were positive on mucicarmine stain, and some neoplastic cells, all the stroma, and associated secretions were positive on alcian blue stain. On immunohistochemistry, the neoplastic cells had strong diffuse cytoplasmic immunoreactivity for cytokeratin and vimentin, weak scattered cytoplasmic immunoreactivity for carcinoembryonic antigen and neuron-specific enolase, and no immunoreactivity for S-100. On the basis of histopathology, histochemistry, and immunohistochemical findings, a diagnosis of mucinous adenocarcinoma of rete testis was made. Rete testis adenocarcinoma is a well known but very rare neoplasm in humans. To our knowledge, this is the first report of the mucinous variant of adenocarcinoma of the rete testis in a dog.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14715972/