Peer-reviewed veterinary case report
Reversible stomach implant tested for weight control in dogs
By Guo, Xiaomei et al.·Published in Obesity surgery·2011·Department of Biomedical Engineering, United States·View original on PubMed →
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Original publication title: Reversible gastric restriction implant: safety and efficacy in a canine model.
- Species:
- dog
Plain-English summary
A group of non-obese dogs underwent surgery to have a reversible implant placed in their stomachs to help them lose weight. Over six weeks, these dogs ate about 38% less food and lost an average of 21% of their body weight without any damage to their stomachs. After the implant was removed, the dogs' weights nearly returned to normal within five weeks. This study suggests that such an implant could be a safe option for helping dogs manage obesity.
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Abstract
BACKGROUND: Gastric restrictive procedures are considered effective weight loss treatment for severe obesity. The aim of the study was to evaluate the efficacy and safety of a reversible implant that renders a partial restriction of stomach in a canine model. METHODS: The device was comprised of two longitudinal parallel non-compressive plates with two C-rings to create a small gastric pouch that opposed gastric distension. Three groups of non-obese mongrel dogs were included: group I (n = 6) underwent surgical implant for 6 weeks, group II (n = 6) underwent surgical implant for 6 weeks, followed by surgical removal of the implant and additional monitoring for 5 weeks, and group III (n = 5) served as sham-operated controls for groups I and II. Food intake and body weight were monitored, and the stomachs were examined histologically postmortem. RESULTS: The average food intake was significantly decreased by 38.2% in group I as compared to group III throughout the 6 weeks of surgical implant (P < 0.05). The implanted dogs showed a progressive weight loss as compared to sham, which reached 21% by the end of 6 weeks. In group II, after 5 weeks of implant removal, the body weights recovered to approximately 96% of baseline. Histological evidence of the implant site at the gastric walls revealed no significant structural changes, tissue ischemia, hemorrhage, or necrosis. CONCLUSION: Our results validate the feasibility of a reversible gastric restriction implant in a non-obese canine model, with the potential for achieving significant weight loss within 6 weeks and with no injury to the gastric wall.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21038085/