Peer-reviewed veterinary case report
Salivary gland basal cell adenocarcinoma: a report of cases in a cat and two dogs.
- Journal:
- Journal of veterinary medicine. A, Physiology, pathology, clinical medicine
- Year:
- 2003
- Authors:
- Sozmen, M et al.
- Affiliation:
- Department of Clinical Veterinary Science · United Kingdom
Plain-English summary
This report discusses a type of cancer called basal cell adenocarcinoma that was found in a cat and two dogs. The tumors were made up of specific types of cells and were tested using special staining methods to identify their characteristics. The findings showed that the tumors had similarities to other salivary gland tumors, and this is the first time this particular cancer has been reported in pets. However, the tests did not help to clearly differentiate it from other types of salivary gland tumors. Overall, the study highlights a new type of tumor in animals but does not provide a unique way to identify it.
Abstract
Basal cell adenocarcinoma of the salivary gland is described in a cat and two dogs; tumour tissue was characterized by cords and islands of epithelial cells with a distinct basal layer. The tumours were stained by various immunohistochemical methods. In addition to positive staining with cytokeratin 14 and pancytokeratin (CKs 5, 6, 8, 17 and 19), there was also staining with Jack bean agglutinin A (ConA) and soya bean agglutinin (SBA); this occurs in many other types of salivary gland tumours and is a feature of normal salivary gland acinar cells. In one dog there was also staining with SBA. This is the first report of this tumour in domestic animals; the immunohistochemical characteristics did not distinguish it from other salivary gland tumours.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/14633217/