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Peer-reviewed veterinary case report

Sebaceous metaplasia in mammary tumor of 8-year-old female Poodle

By Grandi, Fabrizio et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2011·Departamento de Patologia, Brazil·View original on PubMed

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Original publication title: Sebaceous metaplasia in a canine mammary gland non-infiltrative carcinoma with myoepithelial component.

Species:
dog

Plain-English summary

An 8-year-old female Poodle was brought to the vet with a firm, painless lump in her left mammary gland. The tumor was about the size of a marble and had unusual features, including some cells that resembled sebaceous (oil-producing) glands. After examining the tumor, the vet confirmed it was a type of cancer called a non-infiltrative carcinoma. Treatment options would typically include surgery to remove the tumor, and the outcome would depend on the extent of the disease and follow-up care.

People also search for: dog mammary tumor treatment · Poodle cancer symptoms · sebaceous gland tumor in dogs

Abstract

Sebaceous metaplasia in canine mammary tumors is a rare condition with only 1 case documented. The current study describes a case of sebaceous metaplasia in a mammary gland carcinoma of an 8-year-old intact, nulliparous female Poodle dog with a subcutaneous tumor located in the left fifth mammary gland. The lesion measured 0.7 cm × 0.5 cm × 0.6 cm in diameter, was firm, circumscribed, painless, non-haired, and non-ulcerated, and did not adhere to deep tissues. The cut surface was non-lobulated, non-encapsulated, whitish to gray, and opaque. Histological evaluation revealed 3 different populations of cells: the first was composed of columnar to cuboidal malignant epithelial cells arranged in intraductal papillary projections, the second of myoepithelial cells associated with a myxoid stroma, and the third presenting sebaceous metaplasia similar to those previously described in both human and veterinary medicine.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22362808/