Peer-reviewed veterinary case report
Vitamin D levels in dogs with bone cancer are similar to healthy dogs
By Willcox, Jennifer L et al.·Published in Veterinary journal (London, England : 1997)·2016·North Carolina State University, United States·View original on PubMed →
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Original publication title: Serum 25-hydroxyvitamin D concentrations in dogs with osteosarcoma do not differ from those of age- and weight-matched control dogs.
- Species:
- dog
Plain-English summary
A group of dogs with osteosarcoma (a type of bone cancer) had their vitamin D levels tested to see if they were lower than those of healthy dogs of similar age and weight. The results showed that the vitamin D levels in both groups were quite similar, suggesting that low vitamin D may not play a significant role in the development of osteosarcoma in dogs. This means that pet owners shouldn't worry too much about vitamin D levels when it comes to this specific type of cancer.
People also search for: dog osteosarcoma treatment · vitamin D levels in dogs · bone cancer in dogs symptoms
Abstract
Vitamin D concentrations show an inverse correlation with incidence of certain tumors in people and dogs. Additionally, human osteosarcoma has been associated with dysregulation of vitamin D-dependent pathways. The study objective was to compare serum 25-hydroxyvitamin Dand 25-hydroxyvitamin Din 20 dogs with osteosarcoma to age- and weight-matched control dogs. We hypothesized that dogs with osteosarcoma would have lower serum 25-hydroxyvitamin D than control dogs. The mean 25-hydroxyvitamin Dconcentrations for dogs with osteosarcoma and matched-controls were 34.95 ng/mL and 33.85 ng/mL, respectively (P = 0.784). Based on these data, 25-hydroxyvitamin D insufficiency might not be important in the pathogenesis of canine osteosarcoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27810204/