Peer-reviewed veterinary case report
Using glycated albumin to monitor blood sugar in diabetic dogs
By Sako, T et al.·Published in Veterinary research communications·2009·Department of Veterinary Nursing, Japan·View original on PubMed →
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Original publication title: Serum glycated albumin: Potential use as an index of glycemic control in diabetic dogs.
- Species:
- dog
Plain-English summary
A study found that measuring glycated albumin (GA) levels in diabetic dogs can help track their blood sugar control over time. Unlike other tests, GA levels remain stable even during stress or daily fluctuations in blood sugar. This means that GA can provide a reliable indication of how well a dog's diabetes is being managed over a period of 1 to 3 weeks. This could be particularly useful for veterinarians in adjusting insulin treatments for diabetic dogs.
People also search for: diabetic dog blood sugar control · glycated albumin test for dogs · insulin treatment for diabetic dogs
Abstract
Measurements of serum fructosamine, glycated hemoglobin, and glycated albumin (GA) complement serum glucose concentration for better management of diabetes mellitus (DM). Especially, the serum fructosamine test has long been used for diagnosing and monitoring the effect of treatment of DM in dogs. However, fructosamine tests are currently not performed in veterinary medicine in Japan. GA and fructoasmine levels have been shown to strongly correlate. However, the clinical implications of using GA remain to be elucidated. Therefore, the purpose of the current study was threefold: 1) Determine whether GA% is altered by acute hyperglycemia in normal dogs, simulating stress induced hyperglycemia; 2) Demonstrate that GA% does not dynamically change with diurnal variation of blood glucose concentration in diabetic dogs; and 3) Investigate whether GA% is capable of providing an index of glycemic control for 1-3 weeks in diabetic dogs as is the case with diabetic human patients. Our study demonstrated that serum GA% remains very stable and unaltered under acute hyperglycemic conditions (intravenous glucose injection) and in spite of diurnal variation of blood glucose concentration. Furthermore, serum GA% can reflect long-term changes (almost 1-3 weeks) in blood glucose concentration and the effect of injected insulin in diabetic dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19051050/