Peer-reviewed veterinary case report
Dog with severe kidney blood clots linked to lymphoma
By Yabuki, Akira et al.·Published in The Journal of veterinary medical science·2024·Joint Faculty of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Severe glomerular fibrin thrombosis in a dog.
- Species:
- dog
Plain-English summary
A 3-year-old neutered male Chihuahua was brought in with sudden kidney problems, low protein levels, and fluid buildup in the abdomen. The dog also had an enlarged spleen and was diagnosed with B-cell lymphoma, a type of cancer. Despite intensive care, the dog sadly passed away, and tests on the kidneys revealed severe glomerular fibrin thrombosis, which is a condition where blood clots form in the kidney's filtering units. The low protein levels were thought to be the main reason for the kidney damage.
People also search for: Chihuahua kidney problems · dog lymphoma treatment · acute kidney injury in dogs
Abstract
Here, we present a case of severe glomerular fibrin thrombosis in a dog with lymphoma. A 3-year-old neutered male Chihuahua presented with acute kidney injury, hypoalbuminemia, and transudate ascites. The dog showed symmetric enlargement of the spleen, which was diagnosed as B-cell lymphoma based on cytology and polymerase chain reaction tests. The dog died after intensive care, and the kidneys were removed for histopathological examination. Light microscopy, immunofluorescence, and electron microscopy analyses were performed for renal pathology; however, the findings did not support the evidence of protein-losing nephropathy. Instead, the endocapillary accumulation of fibrin thrombi was prominent in most glomeruli. A diagnosis of severe glomerular fibrin thrombosis was established, and hypoalbuminemia was considered the underlying cause of kidney damage.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38057079/