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Peer-reviewed veterinary case report

Severe propofol-associated dystonia in a dog.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2013
Authors:
Mitek, Ashley E et al.
Affiliation:
University of Illinois · United States
Species:
dog

Plain-English summary

A 2-year-old neutered dog was taken to the vet because it had been coughing for a while. After receiving a sedative called propofol through an IV for a procedure, the dog experienced severe muscle stiffness in its neck and front legs while waking up, which didn't respond to treatment but eventually went away on its own after about 25 minutes. The vet suspected this condition was related to the propofol. The case highlights the unusual effects that propofol can have on some dogs.

Abstract

A 2-year-old castrated dog was presented for chronic coughing that was evaluated with bronchoscopy following intravenous boluses of propofol. During recovery the dog developed severe rigidity of muscles of the neck and thoracic limbs, which was unresponsive to treatment but subsided over 25 minutes. A presumptive diagnosis of propofol-associated dystonia was made. The clinical characteristics and theorized pathophysiology of propofol-associated dystonia are discussed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/24155430/