Skunk‐associated rabies case in equine from Northern Mexico

Abstract

Summary A case of equine skunk‐associated rabies was diagnosed in Northern Mexico. A 4‐year‐old mare with clinical signs of ataxia, self‐mutilation, circling, prostration, anorexia, and death 3 days after the onset of the symptoms was reported. History and clinical signs were consistent with a neurological disease. Brain tissue was collected and examined to confirm the diagnosis. The tissue sample was positive for rabies using immunofluorescence assay; whole genome sequencing and viral isolation in suckling mice were performed. Genetic characterisation based on a fragment of the nucleoprotein sequence revealed that a skunk‐associated rabies virus caused infection in the mare. This report is considered important due to it not being related to bat rabies; therefore, identifying the rabies source species has significant implications for public health as well as veterinary consequences. There is a need for greater awareness regarding zoonotic risks, diagnostic assays, prophylactic measures and the establishment of specific procedures to limit horse attacks from rabid wildlife.