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Peer-reviewed veterinary case report

Dog with rare splenic angiomyxoma tumor and blood vessel embolus

By Lee, Eun-Mi et al.·Published in The Journal of veterinary medical science·2016·Department of Pathology, South Korea·View original on PubMed

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Original publication title: Splenic angiomyxoma with intravascular tumor embolus in a dog: a case report.

Species:
dog

Plain-English summary

A 13-year-old male Yorkshire terrier was found to have a large soft mass in his spleen, measuring about 11 cm. This mass was diagnosed as a rare type of tumor called splenic angiomyxoma, which is unusual in dogs and has not been reported in humans. The tumor was causing changes in the spleen's structure and had even formed small clots within blood vessels. Unfortunately, the outcome of the treatment for this specific case isn't provided, but it's important for pet owners to be aware of such rare tumors and discuss any unusual symptoms with their veterinarian.

People also search for: dog spleen tumor symptoms · Yorkshire terrier splenic mass · splenic angiomyxoma treatment

Abstract

A 13-year-old castrated male Yorkshire terrier dog had a soft splenic mass, which measured 11 cm in the greatest diameter. Microscopically, the parenchyma of the spleen was completely replaced by myxoid substances. Numerous spindle and stellate cells were loosely arranged in the myxoid stroma, and variable vessels of variable sizes were observed in a loose matrix with poorly defined margins. Immunohistochemical analysis showed that tumor cells were positive for desmin and alpha-SMA, but negative for S-100. Interestingly, intravascular tumor embolus with positive α-SMA expression was observed. This case is meaningful, because angiomyxoma, a rare tumor of dogs, occurs in the spleen. Even in human cases, splenic angiomyxoma was not reported.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26972144/