Peer-reviewed veterinary case report
Sterile Pyogranulomatous Dermatitis and Panniculitis.
- Journal:
- The Veterinary clinics of North America. Small animal practice
- Year:
- 2019
- Authors:
- Schissler, Jennifer
- Affiliation:
- Department of Clinical Sciences · United States
- Species:
- dog
Plain-English summary
Canine sterile pyogranulomatous dermatitis and panniculitis is a rare skin condition in dogs that causes lumps, sores, and plaques on the skin. The exact cause isn't known, and it can show up with other signs of inflammation, like feeling unwell or having changes in blood tests. Treatment usually involves medication that helps the immune system, and dogs may need to stay on this treatment for life to avoid flare-ups. It's important to rule out other possible skin issues, like infections or tumors, before making a diagnosis. Overall, the treatment is effective, but ongoing management is often necessary to keep the condition under control.
Abstract
Canine sterile pyogranulomatous dermatitis and panniculitis is an infrequently described syndrome. No autoantigen, or exogenous antigen, inflammatory stimulus has been identified. This syndrome is characterized by pyogranulomatous nodules, plaques, and ulcers of variable extent and severity. Prodromal and concurrent nonspecific clinical and hematologic signs of inflammation may occur. This waxing and waning condition is typically responsive to systemic immunomodulation. Lifelong therapy may be required to prevent relapse. Differential diagnoses include bacterial and fungal nodular dermatoses, neoplasia, and cutaneous reactive histiocytosis. Diagnosis is achieved via diagnostic exclusion of infectious causes and supportive histopathology findings.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/30390792/