Peer-reviewed veterinary case report
Dog with skin nodules and ulcers - what is this?
By Schissler, Jennifer·Published in The Veterinary clinics of North America. Small animal practice·2019·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Sterile Pyogranulomatous Dermatitis and Panniculitis.
- Species:
- dog
Plain-English summary
A dog with a skin condition developed painful lumps and sores on its body, which were found to be caused by sterile pyogranulomatous dermatitis and panniculitis. This condition can cause inflammation and requires careful diagnosis to rule out infections or tumors. Treatment typically involves long-term immunosuppressive therapy to manage symptoms and prevent flare-ups. While the condition can be challenging, many dogs respond well to treatment and can lead comfortable lives with ongoing care.
People also search for: dog skin lumps treatment · pyogranulomatous dermatitis in dogs · dog skin sores causes
Abstract
Canine sterile pyogranulomatous dermatitis and panniculitis is an infrequently described syndrome. No autoantigen, or exogenous antigen, inflammatory stimulus has been identified. This syndrome is characterized by pyogranulomatous nodules, plaques, and ulcers of variable extent and severity. Prodromal and concurrent nonspecific clinical and hematologic signs of inflammation may occur. This waxing and waning condition is typically responsive to systemic immunomodulation. Lifelong therapy may be required to prevent relapse. Differential diagnoses include bacterial and fungal nodular dermatoses, neoplasia, and cutaneous reactive histiocytosis. Diagnosis is achieved via diagnostic exclusion of infectious causes and supportive histopathology findings.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30390792/