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Peer-reviewed veterinary case report

Steroid hepatopathy in a horse with glucocorticoid-induced hyperadrenocorticism.

Journal:
Journal of the American Veterinary Medical Association
Year:
1992
Authors:
Cohen, N D & Carter, G K
Affiliation:
Department of Large Animal Medicine and Surgery · United States
Species:
horse

Plain-English summary

A horse was diagnosed with steroid hepatopathy, which is liver damage caused by steroids, after showing signs of a condition called glucocorticoid-induced hyperadrenocorticism (a hormonal imbalance due to steroid use). The horse had symptoms like drinking and urinating a lot, as well as muscle weakness. While being treated, it also developed laminitis, a painful condition affecting the hooves. The outcome of the treatment is not specified in the abstract.

Abstract

Steroid hepatopathy was diagnosed in a horse with glucorticoid-induced hyperadrenocorticism on the basis of anamnesis, serum biochemical data, and histologic findings of hepatic biopsy. Initially, clinical signs of polyuria, polydypsia, and muscular degeneration were seen. The horse developed laminitis during hospitalization.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/1624345/