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Peer-reviewed veterinary case report

Dog mandibular chondroma treated successfully with electrochemotherapy

By Peña, Sara & Ferrer, Otilia R.·Published in Veterinary Record Case Reports·2025·Department of Physiology Faculty of Medicine University of Las Palmas de Gran Canaria Gran Canaria Spain, Spain·View original on Crossref

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Original publication title: Successful management of canine mandibular osteolytic chondroma with electrochemotherapy

Species:
dog

Plain-English summary

A 9-year-old mixed-breed dog was diagnosed with a benign tumor in the jaw called a chondroma, which was causing problems with eating and chewing. Instead of traditional surgery, the vet used a treatment called electrochemotherapy with bleomycin, which is less invasive and well-tolerated. After just one session, the treatment effectively controlled the tumor without the need for surgery, improving the dog's quality of life. This approach shows promise as a safer option for managing similar tumors in dogs.

People also search for: dog jaw tumor treatment · electrochemotherapy for dogs · chondroma in dogs · non-surgical tumor treatment for dogs

Abstract

Abstract In recent years, electrochemotherapy has gained relevance in veterinary oncology for the treatment of locally invasive superficial tumours in dogs, such as mast cell tumours, perianal neoplasms, soft tissue sarcomas, oral squamous cell carcinomas and melanomas. Although chondromas are generally benign, their progressive growth can cause significant anatomical and functional impairments. When located in the mandible, traditional treatment often involves rostral mandiblectomy, which may lead to postoperative sequelae, affecting the animal's quality of life. In this case, electrochemotherapy with bleomycin was well tolerated and achieved effective local tumour control with a single session, without the need for invasive surgery. To the best of our knowledge, this is the first clinical report describing the successful use of electrochemotherapy as a sole therapy for a mandibular chondroma in a dog. This study aimed to explore electrochemotherapy as a less invasive alternative for managing this tumour.

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Original publication on Crossref: https://doi.org/10.1002/vrc2.70198