Peer-reviewed veterinary case report
Metastatic venereal tumor on Dalmatian's mammary skin
By Varughese, E E et al.·Published in Reproduction in domestic animals = Zuchthygiene·2012·Department of Veterinary Gynaecology and Obstetrics, India·View original on PubMed →
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Original publication title: Successful management of metastatic transmissible venereal tumour to skin of mammary region.
Plain-English summary
A female Dalmatian was brought to the vet due to vaginal bleeding and was found to have a transmissible venereal tumor (TVT), which had spread to her skin near the mammary glands. The vet started her on chemotherapy with weekly injections of vincristine. During treatment, she experienced some side effects like a high temperature and changes in her blood cell counts. However, after four weeks of treatment, the tumor and skin nodules disappeared, indicating that she made a full recovery.
People also search for: Dalmatian vaginal bleeding · transmissible venereal tumor treatment · dog skin tumor chemotherapy · vincristine side effects in dogs
Abstract
A Dalmatian female presented with a history of vaginal bleeding and was diagnosed as having transmissible venereal tumour (TVT) after cytological examination of the vaginal growth revealed typical TVT cells. A cytology of the aspirate from multiple nodules in the skin near the abdominal and inguinal pair of mammary glands revealed similar cells suggestive of metastasis to skin of mammary region. Chemotherapy was initiated with weekly injections of vincristine sulphate (0.025 mg/kg BW, IV, SID) and haematological examination was performed pre- and post-treatment to assess the prognosis of the patient and side effects of the drug. The major side effects observed during the course of the treatment were high body temperature, mild neutropaenia and significant decrease in packed cell volume, haemoglobin, total leucocyte and erythrocyte count. Four weekly injections of vincristine were administered, and 4 weeks from initiation of treatment, the tumour and nodules were gone, suggesting complete recovery.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23279540/