Peer-reviewed veterinary case report
Synthesis and in vivo evaluation of 3,4-disubstituted gababutins.
- Journal:
- Bioorganic & medicinal chemistry letters
- Year:
- 2010
- Authors:
- Blakemore, David C et al.
- Affiliation:
- Sandwich Laboratories · United Kingdom
Abstract
A range of 3,4-alkylated five-membered ring derivatives of gabapentin were synthesised. One compound (21) had an excellent level of potency against alpha(2)delta and was profiled in in vivo models of pain and anxiety.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19910190/