Peer-reviewed veterinary case report
Testicular tumor in a 5-year-old XXY dog with Klinefelter syndrome
By Reimann-Berg, Nicola et al.·Published in Cancer genetics and cytogenetics·2008·University of Bremen, Germany·View original on PubMed →
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Original publication title: Testicular tumor in an XXY dog.
- Species:
- dog
Plain-English summary
A 5-year-old dog with Klinefelter syndrome (a genetic condition that can cause low male hormone levels and small testicles) developed a testicular tumor, which is unusual since these tumors typically occur in older dogs. The dog's condition was confirmed through clinical evaluation and genetic testing. This case suggests that the XXY genetic makeup may have led to an earlier onset of the tumor. Treatment details were not provided, but early detection is crucial for managing such conditions.
People also search for: dog testicular tumor symptoms · Klinefelter syndrome in dogs · testicular cancer treatment for dogs
Abstract
Klinefelter syndrome has been described in various species in addition to humans, including cat, pig, horse, and dog. It is associated with low levels of male hormones, sterility, breast enlargement, and small testes. Patients with Klinefelter syndrome have a higher risk for several malignancies. Knowledge about genetic disorders of the dog is comparatively sparse. This is mainly due to the difficult canine karyotypic pattern. We present the case of a canine patient with clinically and cytogenetically confirmed Klinefelter syndrome who developed a testicular tumor at a very early age. Testicular tumors are common in dogs, normally affecting elderly patients (median age, >9 years). In the present case, however, the dog was only 5 years old, allowing the conclusion that the XXY constitution may have promoted the early onset of testicular tumor disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18503830/