Peer-reviewed veterinary case report
Long-term quadruple therapy clears Helicobacter infection
By Khoshnegah, Javad et al.·Published in Journal of feline medicine and surgery·2011·Department of Clinical Sciences·View original on PubMed →
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Original publication title: The efficacy and safety of long-term Helicobacter species quadruple therapy in asymptomatic cats with naturally acquired infection.
- Species:
- cat
Plain-English summary
Thirteen adult stray cats with a Helicobacter species infection were treated with a combination of four antibiotics for 14 days, even though they showed no symptoms. The treatment included medications like omeprazole and amoxicillin, but after the treatment, some cats still had traces of the infection in their stomachs. This suggests that while the antibiotics might temporarily reduce the bacteria, they don't completely eliminate the infection in cats. If your cat has been diagnosed with a Helicobacter infection, it's important to discuss treatment options with your veterinarian, as standard human therapies may not work effectively in cats.
People also search for: cat Helicobacter infection treatment · asymptomatic cat stomach issues · antibiotics for cat stomach infection
Abstract
Owing to rising drug-resistant Helicobacter species infections in people and animals, currently therapies are losing their efficacy; therefore, regimens efficacious in the presence of drug resistance are needed. This study assessed the efficacy and safety of a 14-day quadruple Helicobacter species therapy in cats with naturally acquired infection. Thirteen asymptomatic adult stray cats with Helicobacter species infection (identified by analysis of gastric biopsies using polymerase chain reaction and Helicobacter-specific primers) received omeprazole 0.7mg/kg q 8h plus amoxicillin 20mg/kg q 12h, metronidazole 20mg/kg q 12h and clarithromycin 7.5mg/kg q 12h, for 14 days. Second molecular analysis of gastric biopsies revealed persistence of Helicobacter species DNA in four cats that were negative on quantitative urease testing, cytology and histopathology. Our results suggest that antibiotic regimens that are effective against Helicobacter pylori in people cannot eradicate Helicobacter species in cats with naturally acquired infection, although transient suppression may occur.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21144784/