Peer-reviewed veterinary case report
Cat developed low platelets after G-CSF treatment that resolved
By Kim, Kyeong-Bo et al.·Published in Veterinary medicine and science·2022·Department of Veterinary Clinical Science, South Korea·View original on PubMed →
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Original publication title: Transient thrombocytopenia in a cat following G-CSF treatment.
- Species:
- cat
Plain-English summary
A 4-year-old Russian blue cat with idiopathic epilepsy was treated for low white blood cell counts (neutropenia) using a medication called granulocyte colony-stimulating factor (G-CSF). After completing the treatment, the cat developed a severe drop in platelets (thrombocytopenia), which is likely linked to the G-CSF. Fortunately, the cat did not need any additional treatment, and the platelet levels returned to normal on their own within two weeks. This case highlights a rare side effect of G-CSF in cats.
People also search for: cat low platelet count treatment · Russian blue cat neutropenia · G-CSF side effects in cats
Abstract
A 4-year-old, castrated male, Russian blue cat with idiopathic epilepsy was diagnosed with neutropenia. The neutropenia was classified as idiopathic after blood tests and abdominal imaging did not reveal an infectious, inflammatory or neoplastic aetiology. As a treatment trial for idiopathic neutropenia, the cat was administered granulocyte colony-stimulating factor by subcutaneous injection once daily for 3 days. Two weeks after completion of granulocyte colony-stimulating factor therapy, the cat developed severe thrombocytopenia, with the granulocyte colony-stimulating factor therapy considered to be the most likely cause. No treatment was initiated, and the thrombocytopenia had resolved spontaneously by 2 weeks after diagnosis. This is the first reported case of transient severe thrombocytopenia in a cat following granulocyte colony-stimulating factor treatment.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34967142/