Peer-reviewed veterinary case report
Dog with leg paralysis from tumor clot treated with artery
By Kim, Jung-Hyun & Park, Hee-Myung·Published in The Journal of veterinary medical science·2012·BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, South Korea·View original on PubMed →
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Original publication title: Unilateral femoral arterial thrombosis in a dog with malignant mammary gland tumor: clinical and thermographic findings, and successful treatment with local intra-arterial administration of streptokinase.
- Species:
- dog
Plain-English summary
An 8-year-old female dog suddenly lost the ability to use her back leg and was diagnosed with a blood clot in the artery, likely caused by a malignant mammary gland tumor. Despite initial treatment with a common clot-busting medication given through an IV not working, the vet then delivered the medication directly to the site of the clot. This targeted approach successfully restored blood flow and helped the dog regain use of her leg. The case also highlighted how thermography can help identify the location of such clots.
People also search for: dog hind leg paralysis · malignant mammary tumor treatment · blood clot in dog leg · streptokinase for dogs
Abstract
An 8-year-old intact female dog presented with a sudden onset of unilateral hindlimb paralysis of 3 days duration. Based on the history and results of physical, neurological, and histopathological examinations, and blood work, an arterial thrombosis was suspected as a complication of the hypercoagulability from a malignant mammary gland tumor. Thermography provided evidence of the unilateral femoral thrombus. Initially, thrombolysis with streptokinase administered by intravenous infusion was ineffective. Thereafter, the direct delivery of streptokinase to the site of thrombus was attempted. The approach was curative. These results suggest that thermography could describe the site of the arterial thrombus, and local intra-arterial administration of streptokinase may be an effective therapy for the canine arterial thrombosis complicated by malignant mammary gland tumor.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22185771/