Peer-reviewed veterinary case report
Labrador with lung mass diagnosed by oestradiol after sertoli cell
By Gopinath, D et al.·Published in The Journal of small animal practice·2009·University of Glasgow, United Kingdom·View original on PubMed →
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Original publication title: Use of intralesional oestradiol concentration to identify a functional pulmonary metastasis of canine sertoli cell tumour.
- Species:
- dog
Plain-English summary
A 7-year-old neutered male Labrador was brought in for signs of feminization and prostate issues, four years after having a testicular tumor removed. Tests showed high levels of a hormone called oestradiol in his blood and in a fluid-filled mass in his lungs. The mass was surgically removed and confirmed to be a metastasis (spread) of the original testicular tumor. This case is notable because it’s the first time a lung metastasis from a Sertoli cell tumor has been identified using hormone measurement.
People also search for: dog lung tumor treatment · Labrador feminization syndrome · Sertoli cell tumor in dogs
Abstract
A seven-year-old, 31 kg male neutered Labrador was investigated for signs of feminisation syndrome and prostatic disease four years after castration and removal of a testicular sertoli cell tumour (SCT). Investigations revealed an elevated serum oestradiol-17beta concentration, a pulmonary mass containing fluid high in oestradiol-17beta and cystic changes in the prostate gland. The pulmonary mass was surgically excised and histologically confirmed to be a SCT metastasis. To the authors' knowledge, this is the first reported case of a proven functional extranodal SCT metastasis and the first to be diagnosed by oestradiol-17beta measurement of intralesional fluid.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19037884/