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Peer-reviewed veterinary case report

Dog with spinal mass causing kyphosis and tremors diagnosis

By Khachatryan, Artashes R et al.·Published in Veterinary clinical pathology·2009·College of Veterinary Medicine, United States·View original on PubMed

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Original publication title: What is your diagnosis? Vertebral mass in a dog.

Species:
dog

Plain-English summary

A 1-year-old mixed-breed dog was brought to the vet because he was having episodes of back arching, tremors, and vocalizing. An MRI revealed a large mass in his spine, and tests showed it was a type of tumor called myxosarcoma. Unfortunately, the condition was severe, leading to significant spinal cord compression, and the decision was made to euthanize him. This case highlights the importance of considering myxosarcoma when a young dog has a spinal mass.

People also search for: dog back pain tremors · myxosarcoma in dogs · dog spinal tumor symptoms

Abstract

A 1-year-old, castrated male, mixed-breed dog was presented for sporadic episodes of kyphosis, tremors, and vocalizing. On neurologic examination, the lesion was localized to spinal cord segments T3-L3. Magnetic resonance imaging of the spine showed an expansile mass occupying most of the ventral aspect of the spinous process of T6. Fine-needle aspirates of the mass were examined cytologically. A moderately cellular population of pleomorphic spindle cells and abundant mucinous matrix were observed. The cytologic diagnosis was spindle cell neoplasia, with myxosarcoma and fibrosarcoma as the primary differential diagnoses. The dog was euthanized. Histopathologic evaluation of the mass and surrounding tissue confirmed a low-grade spindle cell sarcoma, with severe compressive myelopathy and mild neutrophilic inflammation. The neoplastic cells stained positive for mucopolysaccharides with Alcian blue, resulting in a final diagnosis of low-grade (grade 1) myxosarcoma. Fine-needle aspiration was useful in making a preliminary diagnosis of myxosarcoma in this case. Myxosarcoma should be included in the differential diagnosis for a vertebral mass in a young dog.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19490569/