Peer-reviewed veterinary case report
Kidney damage from calcium oxalate crystals in a 3-month-old cat
By Suzuki, Takayuki et al.·Published in The Journal of veterinary medical science·2012·Nippon Institute for Biological Science, Japan·View original on PubMed →
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Original publication title: A case of renal oxalosis in a 3-month-old cat raised under controlled conditions.
- Species:
- cat
Plain-English summary
A 3-month-old female cat was brought in for progressive weight loss and abnormal kidney function, indicated by high blood levels of urea and creatinine. Upon examination, the vet found that both kidneys were firm and had developed scars, along with the presence of calcium oxalate crystals, which can cause kidney damage. This condition, known as renal oxalosis, was suspected to be hereditary. Unfortunately, the cat's prognosis was not detailed, but early detection and treatment are crucial for managing kidney issues in pets.
People also search for: kitten weight loss · cat kidney problems · calcium oxalate crystals in cats · hereditary kidney disease in cats
Abstract
The kidneys of a 3-month-old female cat were examined. The cat which had been raised under controlled conditions with no history of any poisoning showed progressive weight loss with increases in blood BUN and creatinine concentrations. At necropsy, both kidneys were firm in consistency with formation of focal scars. Histopathologically, widespread deposition of crystals was observed in the renal tubules (in both dilated lumina and degenerative epithelia) accompanying mild interstitial fibrosis with lymphocyte infiltration. The crystals were colorless or basophilic on the hematoxilin and eosin-stained section and could be visualized with polarized light as doubly fractile crystals. The crystals were identified as calcium oxalate crystals by histochemical examinations using von Kossa stain and alizarin red S stain under different conditions and by ultrastructural examination. Judging from the above-mentioned findings, the present renal lesion detected in an infant cat was diagnosed as renal oxalosis which was suspected to be hereditary in nature.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22067080/