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Peer-reviewed veterinary case report

Ameloblastomas in the horse: a critical review and report of an additional example.

Journal:
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Year:
1994
Authors:
Gardner, D G
Affiliation:
University of Colorado School of Dentistry
Species:
horse

Plain-English summary

This study looks at a rare type of tumor called ameloblastoma in horses, reviewing past cases and adding a new one. Ameloblastomas can show two different patterns under a microscope: one has clusters of cells that look like the tumor's typical features, while the other has cells that are more tightly packed and shaped differently. The behavior of these tumors in horses seems to be similar to how they act in people, growing slowly and invading nearby tissues without spreading to other parts of the body. However, more research is needed to confirm this.

Abstract

Previously published cases of ameloblastoma in the horse are reviewed in detail for their acceptability as examples of that tumor; an additional one is described. So far, this rare equine lesion has been shown to have two histologic patterns. The first consists of islands and sheets of epithelium that exhibit the basal cell characteristics of ameloblastoma; the central cells comprise stellate reticulum. The second exhibits these basal cell features less markedly and the central cells are spindle-shaped and closely packed. The biologic behavior of the equine ameloblastoma is thought to be the same as in human beings, a slowly growing, invasive lesion that does not metastasize. However, this conclusion requires confirmation.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/8138980/