Peer-reviewed veterinary case report
Brain tumor ganglioneuroblastoma in 8-month-old Golden Retriever
By Kuwamura, M et al.·Published in Veterinary pathology·2004·Osaka Prefecture University, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Cerebral ganglioneuroblastoma in a golden retriever dog.
- Species:
- dog
Plain-English summary
An 8-month-old Golden Retriever was sadly euthanized due to a large brain tumor affecting the right side of its brain. The tumor, called a cerebral ganglioneuroblastoma, was made up of both mature and immature nerve cells. This type of tumor is extremely rare in dogs and had never been reported in this location before. Unfortunately, the condition was severe enough that the decision was made to end the dog's suffering.
People also search for: dog brain tumor symptoms · Golden Retriever euthanasia · rare dog tumors · puppy neurological issues
Abstract
An 8-month-old Golden Retriever dog was euthanatized because of a large cerebral mass extending from the right frontal lobe to the thalamus that was composed of both mature and immature neuronal cells. The better differentiated cells had abundant eosinophilic cytoplasm with prominent Nissl substance and were generally positive for neurofilament and variably positive for synaptophysin. The generally smaller and less-differentiated cells were infrequently positive for proliferating cell nuclear antigen and were negative for any neuronal and glial markers. No apparent glial differentiation of the immature tumor cells was detected. Based on morphologic and immunohistochemical features, the diagnosis of cerebral ganglioneuroblastoma was made. This neoplasm is very rare in all species, especially in the central nervous system, and has never been reported previously in this site in a dog.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15133180/