Peer-reviewed veterinary case report
Gliomatosis cerebri in a dog.
- Journal:
- Journal of veterinary medicine. A, Physiology, pathology, clinical medicine
- Year:
- 2006
- Authors:
- Gruber, A et al.
- Affiliation:
- Department of Pathobiology
- Species:
- dog
Plain-English summary
A 9-year-old male flat-coated retriever was diagnosed with gliomatosis cerebri, a rare type of brain tumor that affects the central nervous system. The dog showed signs of central nervous system issues, and an MRI scan revealed unclear areas in the right side of the brain, brainstem, and cerebellum. A closer look at the brain tissue confirmed the presence of tumor cells. The diagnosis was made based on these imaging and tissue examination results. Unfortunately, the outcome of the treatment is not specified in the report.
Abstract
Gliomatosis cerebri is a rare tumourous disease of the central nervous system consisting of glial cells characterized by diffuse widespread infiltration and preservation of preformed brain structures. This report describes a case of gliomatosis cerebri in a 9-year-old, male, flat-coated retriever dog with central nervous symptoms. Magnetic resonance imaging of the brain demonstrated ill-defined hyperintense zones of paramedian white matter within the right cerebral hemisphere, brainstem and cerebellum. Histological examination showed a proliferation of tumour cells in the brain structures mentioned. Glial fibrillary acidic protein-immunohistochemistry revealed a lot of fibres positively stained. Based on these findings, the alteration was diagnosed as gliomatosis cerebri.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16970635/