Peer-reviewed veterinary case report
Granulomatous colitis: more than a canine disease? A case of -associated granulomatous colitis in an adult cat
- Journal:
- Journal of Feline Medicine and Surgery Open Reports
- Year:
- 2017
- Authors:
- Rodolfo Oliveira Leal et al.
- Affiliation:
- Fregis Veterinary Health Centre, Arcueil, France · GB
Plain-English summary
This report discusses a 4-year-old cat that had been experiencing intermittent episodes of blood in its stool and problems controlling its bowel movements for the past seven months. Tests showed that the cat had severe ulcers in its colon and a large number of certain immune cells in the affected area. Further analysis of tissue samples revealed clusters of a type of bacteria called Escherichia coli that can invade the intestinal lining. After treating the cat with antibiotics for six weeks, all of its symptoms completely went away. This case highlights that certain bacteria can cause serious intestinal issues in cats, suggesting that vets should test for these infections when diagnosing similar problems.
Abstract
Case summary This report describes a 4-year-old cat with chronic intermittent haematochezia and faecal incontinence of 7 months’ duration. Investigation revealed severe colonic multifocal mucosal ulcerations and infiltration of the mucosal lamina propria by large numbers of periodic acid–Schiff-positive macrophages. Fluorescence in situ hybridisation analysis of colonic biopsies revealed multifocal clusters of intracellular Escherichia coli . Treatment with fluoroquinolones for 6 weeks led to a complete resolution of clinical signs. Relevance and novel information The findings reveal that mucosally invasive E coli can also be associated with granulomatous colitis in cats and indicate the need for diagnostic testing of mucosal samples for E coli and other infectious agents.
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Search related cases →Original publication: https://doi.org/10.1177/2055116917731168