Peer-reviewed veterinary case report
Hemangiopericytoma in the eyelid of a horse.
- Journal:
- Veterinary pathology
- Year:
- 2006
- Authors:
- Serena, A et al.
- Affiliation:
- Department of Clinical Sciences · United States
Plain-English summary
A 14-year-old female Arabian horse was brought in for surgery to remove a 2-centimeter-wide mass on her right lower eyelid. This mass was identified as a hemangiopericytoma, which is a type of tumor that comes from certain cells around blood vessels. The tumor had a specific appearance under the microscope and showed particular reactions to certain tests that helped confirm its diagnosis. This case is notable because it is the first time a hemangiopericytoma has been reported in a horse. The treatment involved surgically removing the tumor, and while the outcome isn't specified, the diagnosis itself is an important finding in veterinary medicine.
Abstract
Hemangiopericytoma (HP) is a well-recognized neoplasm arising from vascular pericytes that has been reported only in the dog and man. In this study, we describe a 14-year-old female Arabian horse that was presented for surgical excision of a 2-cm-diameter expansile subcuticular mass in the right lower eyelid. Histologically, the mass consisted of loosely arranged interlacing streams and storiform bundles of spindle cells that often formed distinct whorls around a central capillary and bundles of collagen (Antoni A-like pattern). Immunohistochemical analysis revealed strong diffuse cytoplasmic immunoreactivity for vimentin and focal immunoreactivity for smooth muscle actin, whereas neoplastic cells did not stain for Factor VIII-related antigen, Glial fibrillary acidic protein (GFAP), or S100. On the basis of histomorphology and immunohistochemical reactivity, the present tumor was diagnosed as HP. To our knowledge, this is the first report describing a HP in a horse.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16847005/