Peer-reviewed veterinary case report
Recombinant canine coronaviruses related to transmissible gastroenteritis virus of Swine are circulating in dogs.
- Journal:
- Journal of virology
- Year:
- 2009
- Authors:
- Decaro, Nicola et al.
- Affiliation:
- Department of Public Health and Animal Sciences · Italy
- Species:
- dog
Abstract
Four canine coronavirus type II (CCoV-II) strains were identified in the guts and internal organs of pups which had died of acute gastroenteritis. The CCoV-II strains were strictly related to porcine transmissible gastroenteritis virus (TGEV) in the N-terminal domain of the spike protein, whereas in the other parts of the genome, a higher genetic relatedness to recent CCoV-II isolates was observed. Experimental infection of dogs with a TGEV-like isolate induced mild gastroenteritis without any systemic involvement. By virus neutralization tests, antigenic differences between reference and TGEV-like CCoVs were found. Our data support the potential recombinant origin of the TGEV-like CCoVs.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19036814/